Bone Marrow Transplantation

Haematopoietic Stem Cell Transplant (Bone Marrow Transplant)

Bone Marrow is a soft, spongy substance that is found in the centre of our bones and contains stem cells. These stems cells produces all types of blood cells and immune cells. Sometimes, because of blood cancer or genetic or acquired defects bone marrow is not able to work properly. In order to restore normal bone marrow function, a Bone Marrow Transplant procedure is required. A Bone Marrow Transplant replaces damaged or dead stem cells with healthy cells. However, this is non-surgical procedure when compared to some of the other organs transplant procedures like kidney or lungs. This procedure can benefit people who suffer from cancerous or non-cancerous type of diseases.

Types of Bone Marrow Transplants

Medical excellence in the country is now on par with International Standards as our doctors keep themselves updated on the latest developments in Medical
Science and upgrade their skillsets.Bone Marrow Transplants can be categorised into two types:

Autologous Stem Cell Transplant

In this process, the stem cells are extracted from the same person who is scheduled to undergo the procedure. Auto, which also means self, sees the patient himself becoming the donor as well. The major advantage with the Autologous Stem Cell Transplant procedure is that the patient gets his own cells back. As a result, the percentage of rejection of cells is zero. Doctors usually recommend this type of transplant procedure to treat certain types of lymphomas and multiple myeloma, autoimmune disorders, multiple sclerosis.

Allogeneic Stem Cell Transplant

As the name indicates, Allo means other. Hence, in this case of transplant procedure, the stem cells are extracted from another donor. The donor can be a related donor whose stem cells might match or an unrelated donor. The main advantage of this type of transplant is that the donor can be requested to donate more stem cells if required. Stem cells from healthy donors are free from cancer cells. Doctors usually recommend this type of transplant procedure to treat certain types of acute leukemias, bone marrow failure syndromes, apalstic anemia, immunodeficiency disorders, thalassemia. To the surprise, for majority of hematological disorders this is only the cure.

Before the Transplant, After the Transplant

Before

  • Before undergoing the procedure, Hematologist will recommend certain medical tests to ascertain your fitness to take up
    the procedure.
  • If you are scheduled to undergo a transplant using your own stem cells, then you will have to go through a procedure to col-
    lect the stem cells.
  • If you are scheduled to undergo a transplant using donor cells, then you will have to wait till the right donor is found and stem
    cells are collected. For this HLA testing of patient and donor is required. Blood group match is not must.
  • Once you are certified as fit to take up the procedure, before the actual procedure begins, you will have to undergo another
    process called as conditioning, where you will receive chemotherapy, immunotherapy and possibly, radiation.

After

  • You will require hospitalization for a specific number of days, day 2 to 4 weeks depending on the risk factors involved.
  • Your doctor will prescribe the necessary medications after closely monitoring your health condition.
  •  You will slowly be able to resume physical activity to strengthen your bones.

Our Bone Marrow Transplant Specialist

Dr. S.K. Gupta is a well-known Haematologist in India, practicing at Haematology and BMT Institute International. He has an extensive experience of over 15 years and has successfully performed over 250 Bone Marrow Transplant procedures on patients in India and Overseas. He leads a team of distinguished and experienced doctors who are collectively well-versed in treating all types of Haematological disorders. Dr. Gupta puts patients above anything else and his calm and accommodative approach comforts patients and instils more confidence in them. He continues to be an inspiration for aspiring young doctors.

For excellent guidance on Bone Marrow Transplant, feel free to connect with Haematology and BMT Institute.

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