Dr. S.K. Gupta is one of the Best Pancytopenia Specialists in Hyderabad. He is a renowned Hematologist in India with extensive experience of over 15 years in the field of Hematology. Moreover, proper monitoring of the patient’s condition, boosting the morale of both patient as well family are also key steps in reducing the morbidity and mortality during the treatment which Dr. S.K. Gupta takes care at a personal level along with his strong supportive team. At the same time, he is running a lot of awareness camps at the community level for the same to benefit all age groups of patients ranging from new-born to elderly.
What is Pancytopenia?
Pancytopenia refers to the combination of anemia, leukopenia, and thrombocytopenia. Causes may be due to bone marrow failure, bone marrow infiltration, ineffective hematopoiesis or peripheral pooling/destruction. A bone marrow aspirate is usually required to establish the diagnosis. Aetiologies of pancytopenia vary from one geographical region to others.
Various etiological factors have been implicated in the causation of pancytopenia. Major factors include a reduction in blood cell production, infiltration of bone marrow (BM) by abnormal cells, suppression of BM, ineffective hematopoiesis with cell destruction, antibody-mediated destruction of cells, and sequestration of cells in the reticuloendothelial system. Treatment and prognosis of patients with pancytopenia are governed by the cause and severity of the underlying disease.
Pancytopenia is caused by various conditions. There are various predisposing factors for these anemias like alcoholism, hypothyroidism, self-limiting illnesses, puberty, pregnancy.
Therefore it is necessary to treat such cases with iron and/or vitamin B12/folate, to repeat hemogram after a few weeks and if necessary further evaluation with an invasive procedure like bone marrow may be considered.
There are other treatable causes like dengue, malaria, enteric fever, and TB. In such cases, pancytopenia resolves over sometime after etiology specific treatment is given. However, the bone marrow becomes necessary if there is no improvement or there are signs which are suggestive of severe diseases like leukemia, MDS, etc.
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